HORIZON-HLTH-2027-03-TOOL-04

Virtual Human Twins for clinical decision support

Integrated virtual-human-twin solutions supporting prevention and diagnosis through validated, interoperable clinical decision tools. This briefing highlights the opportunity at a practical level; the official topic conditions remain binding.

HORIZON-HLTH-2027-03-TOOL-04

Virtual Human Twins for clinical decision support

Integrated virtual-human-twin solutions supporting prevention and diagnosis through validated, interoperable clinical decision tools.

Type of actionResearch and Innovation Action (RIA)Opening2 June 2027Deadline22 September 2027ProgrammeCluster 1 · Health

Core intervention logic

  1. 1Select the clinical challengeIntegrate multiscale models and health data into Virtual Human Twins
  2. 2Integrate models and dataValidate decision-support solutions in relevant prevention or diagnostic settings
  3. 3Validate decision supportAdvance interoperability, usability, trust and clinical adoption
  4. 4Prepare adoptionIntegrate multiscale models and health data into Virtual Human Twins

How the action works

Starting point
Select the clinical challenge
Integrate models and dataValidate decision support
Prepare adoption

More personalised and evidence-based prevention and diagnosis.

Expected impactMore personalised and evidence-based prevention and diagnosis.Stronger European collaborationEvidence that supports uptakeValue beyond the grant
Key message:Integrated virtual-human-twin solutions supporting prevention and diagnosis through validated, interoperable clinical decision tools.EXELIXIS Research Management & Communication
A practical visual reading of the call’s intervention logic, consortium needs, expected outputs and route to impact.

Who is it for?

Clinical and biomedical research organisations; Modelling, simulation, AI and data-technology teams; Hospitals, patient organisations, SMEs and technology developers. The strongest consortia will connect these capabilities around a clearly defined need rather than assemble partners only to satisfy formal eligibility.

What does the call support?

Integrate multiscale models and health data into Virtual Human Twins.

Validate decision-support solutions in relevant prevention or diagnostic settings.

Advance interoperability, usability, trust and clinical adoption.

What are the key requirements?

Proposal perspective

A competitive proposal must connect the topic’s expected outcomes to a focused intervention logic, credible partners, measurable results and a convincing route to uptake. Scope, eligibility and all special conditions should be checked against the official topic text before consortium commitments are made.

Timeline and next steps

The topic is scheduled to open on 2 June 2027 and the deadline is 22 September 2027. Prospective applicants should use the preparation period to confirm fit, shape the core concept, identify the capabilities required and build the work plan around the expected outcomes.

EXELIXIS can support call interpretation, concept positioning, consortium architecture, proposal development, impact pathways and coordination of partner contributions.

Official sources

This briefing is an original summary prepared from official EU sources. It is provided for orientation and does not replace the binding call text, General Annexes or Funding & Tenders Portal conditions.