HORIZON-HLTH-2027-01-DISEASE-08

Innovative antimicrobials against resistant pathogens

Developing urgently needed antimicrobial candidates against critical pathogens and advancing them towards clinical use. This briefing highlights the opportunity at a practical level; the official topic conditions remain binding.

HORIZON-HLTH-2027-01-DISEASE-08

Innovative antimicrobials against resistant pathogens

Developing urgently needed antimicrobial candidates against critical pathogens and advancing them towards clinical use.

Type of actionResearch and Innovation Action (RIA)Opening9 February 2027Deadline13 April 2027ProgrammeCluster 1 · Health

Core intervention logic

  1. 1Prioritise the pathogenDiscover or advance innovative antimicrobial approaches
  2. 2Advance the candidateGenerate robust preclinical and translational evidence
  3. 3Generate translational evidenceAddress resistance, stewardship and future clinical development
  4. 4Prepare clinical developmentDiscover or advance innovative antimicrobial approaches

How the action works

Starting point
Prioritise the pathogen
Advance the candidateGenerate translational evidence
Prepare clinical development

A stronger antimicrobial pipeline against high-priority resistant infections.

Expected impactA stronger antimicrobial pipeline against high-priority resistant infections.Stronger European collaborationEvidence that supports uptakeValue beyond the grant
Key message:Developing urgently needed antimicrobial candidates against critical pathogens and advancing them towards clinical use.EXELIXIS Research Management & Communication
A practical visual reading of the call’s intervention logic, consortium needs, expected outputs and route to impact.

Who is it for?

Infectious-disease and antimicrobial researchers; Clinical, microbiology and translational-development teams; Biotechnology, pharmaceutical and regulatory partners. The strongest consortia will connect these capabilities around a clearly defined need rather than assemble partners only to satisfy formal eligibility.

What does the call support?

Discover or advance innovative antimicrobial approaches.

Generate robust preclinical and translational evidence.

Address resistance, stewardship and future clinical development.

What are the key requirements?

Proposal perspective

A competitive proposal must connect the topic’s expected outcomes to a focused intervention logic, credible partners, measurable results and a convincing route to uptake. Scope, eligibility and all special conditions should be checked against the official topic text before consortium commitments are made.

Timeline and next steps

The topic is scheduled to open on 9 February 2027 and the deadline is 13 April 2027. Prospective applicants should use the preparation period to confirm fit, shape the core concept, identify the capabilities required and build the work plan around the expected outcomes.

EXELIXIS can support call interpretation, concept positioning, consortium architecture, proposal development, impact pathways and coordination of partner contributions.

Official sources

This briefing is an original summary prepared from official EU sources. It is provided for orientation and does not replace the binding call text, General Annexes or Funding & Tenders Portal conditions.