Developing urgently needed antimicrobial candidates against critical pathogens and advancing them towards clinical use. This briefing highlights the opportunity at a practical level; the official topic conditions remain binding.
Innovative antimicrobials against resistant pathogens
Developing urgently needed antimicrobial candidates against critical pathogens and advancing them towards clinical use.
Core intervention logic
- 1Prioritise the pathogenDiscover or advance innovative antimicrobial approaches
- 2Advance the candidateGenerate robust preclinical and translational evidence
- 3Generate translational evidenceAddress resistance, stewardship and future clinical development
- 4Prepare clinical developmentDiscover or advance innovative antimicrobial approaches
How the action works
Prioritise the pathogen
A stronger antimicrobial pipeline against high-priority resistant infections.
Who is it for?
Infectious-disease and antimicrobial researchers; Clinical, microbiology and translational-development teams; Biotechnology, pharmaceutical and regulatory partners. The strongest consortia will connect these capabilities around a clearly defined need rather than assemble partners only to satisfy formal eligibility.
What does the call support?
Discover or advance innovative antimicrobial approaches.
Generate robust preclinical and translational evidence.
Address resistance, stewardship and future clinical development.
What are the key requirements?
- Focus on pathogens and unmet needs specified by the topic
- A credible development pathway with relevant models and endpoints
- Industrial, clinical and regulatory expertise appropriate to translation
- Action type: Research and Innovation Action (RIA).
A competitive proposal must connect the topic’s expected outcomes to a focused intervention logic, credible partners, measurable results and a convincing route to uptake. Scope, eligibility and all special conditions should be checked against the official topic text before consortium commitments are made.
Timeline and next steps
The topic is scheduled to open on 9 February 2027 and the deadline is 13 April 2027. Prospective applicants should use the preparation period to confirm fit, shape the core concept, identify the capabilities required and build the work plan around the expected outcomes.
EXELIXIS can support call interpretation, concept positioning, consortium architecture, proposal development, impact pathways and coordination of partner contributions.
Official sources
This briefing is an original summary prepared from official EU sources. It is provided for orientation and does not replace the binding call text, General Annexes or Funding & Tenders Portal conditions.
